Background:

The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

Applications:

ELISA, WB, IHC

Name of antibody:

MCM5

Immunogen:

Fusion protein of human MCM5

Full name:

minichromosome maintenance complex component 5

Synonyms:

CDC46; P1-CDC46

SwissProt:

P33992

IHC positive control:

Human gastric cancer and human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

82 kDa

WB Positive control:

HepG2, K562, Jurkat, 231 and hela cells

WB Recommended dilution:

500-2000